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Grease two 9-in. round cake pans and line the bottom with parchment paper; set aside.
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In a small saucepan, heat beer and butter until butter is melted. Remove from the heat; whisk in sugar and cocoa until blended.
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Combine the eggs, sour cream and vanilla; whisk into beer mixture. Combine flour and baking soda; whisk into beer mixture until smooth.
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Pour batter into prepared pans.Bake at 350° for 45-50 minutes or until a toothpick inserted near the center comes out clean. Cool completely in pan on a wire rack.
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Meanwhile, make the glaze by heating butter, sugar and whiskey in a small saucepan over low heat. Whisk constantly until butter melts and sugar dissolves.
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Carefully slice each layer of cake horizontally to create 4 cake layers.
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Brush each layer generously with whiskey glaze. Allow to absorb for at least 20 minutes.
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Meanwhile make the frosting by beating together butter, 4 cups powdered sugar, Bailey's Irish Cream and vanilla extract in large mixing bowl until well combined. Add additional powdered sugar 1/2 cup at a time until desired consistency is achieved.
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Spread one cake layer with frosting. Stack another layer on top and repeat until all layers are stacked. Spread the top and sides of the cake with frosting.
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Slice and enjoy!